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IVM - In Vitro Maturation

What is IVM?

In classical IVF treatment, the eggs are collected and processed after maturation. In IVM treatment, eggs collected before maturation and they are matured in the laboratory. The aim of this treatment is not to give the medications used to mature the eggs to the patient and to protect their bodies. During IVM treatment, a small amount of hormone may be given to the patient.

The collected eggs are kept in certain liquids in the laboratory and matured. In the next step, the sperm from the male is injected into the eggs by microinjection method and the obtained embryos are put back into the uterus as the last step.

Who should choose IVM?

It has been seen that some of the patients are sensitive to the medications which is used in IVF treatment, and this may cause fluid accumulation in the abdomen and lungs and ovarian hyperstimulation syndrome (OHSS). In Vitro Maturation is especially preferred in patients with PCOS (Polycystic Ovary Syndrome) who have this sensitivity and high probability of developing OHSS. It can also be used in patients with endometriosis, with poor response to medications, and in male infertility.

IVM treatment is an ideal method for cancer patients where hormone therapy is strictly prohibited.

What are the advantages?

  • Treatment is easier than IVF
  • Duration of the treatment is shorter than (8-10 days)
  • It has no side effects
  • It does not cause complications
  • It requires less clinical visits for the patient (1-2 times)
  • It reqiures less injection (2-3 injections)
  • There is no need to take blood

What are the disadvantages?

During treatment, eggs of the desired quality may not always be obtained. And pregnancy rates are slightly lower.

Who can not have IVM?

Patients with advanced age can not have IVM treatment.

What is the success rate?

The success rates of IVM are 30% and are within acceptable success limits.

How long is the treatment period?

IVM treatment lasts 8 to 10 days.