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IUI – Intrauterine Insemination

What is IUI?

The process of injecting sperm from the male into the uterus of the woman during ovulation is called vaccination. This treatment is recommended for couples having problems in fertilizing the egg cell by passing the sperm into the tubes through the uterus.

Who can have Vaccination Therapy?

  • Patients with insufficient sperm number, structure and mobility
  • Patients with erectile dysfunction
  • Patients with retrograde ejaculation (ejaculation in the opposite direction of the penis instead of the tip)
  • Female patients with antibodies that damage sperm cells
  • Patients with moderate endometriosis
  • Patients with unexplained infertility

In order for vaccination to be performed, at least one of the patient’s tubes must be open, and the number and structure of sperm cells must be within the values ​​at which vaccination can be performed.

During the vaccination period, external medication is given to stimulate the ovaries. The aim of these drugs is to ensure a healthy follicle development in the ovaries.

Egg Development Monitoring

Egg development is monitored by hormone analysis and ultrasonography (USG). The size of the egg cell is monitored by ultrasonography. When the follicle size is around 17-18 mm, it is ready to crack. In hormone analysis, estrogen and LH hormones are measured. The increase in estrogen hormone indicates a healthy follicle development. The hormone LH shows a sudden increase in the ovulation period, causing the follicle to crack and release the egg cell. After the released egg cell passes into the tubes, it is fertilized by the sperm cell. These measurements are very important in monitoring egg development.

  • Painkillers should not be used unless they are very needed in the near ovulation period.
  • Sexual life can be continued during the treatment process.
  • Radiation should be avoided (X-ray film, etc.).

Vaccination Time

On the day of vaccination, the sperm sample taken from the man is subjected to a series of procedures and the sperm cells which are most likely to fertilize the egg cell are separated and injected into the uterus.

What are the Risks of Treatment?

  • Since the drugs used for vaccination can cause multiple follicles to develop in the ovaries, there is an increase in the rate of multiple pregnancies.
  • The ovaries can sometimes over-respond to the medications used, which can cause growth in the ovaries and accumulation of water in the abdomen.
  • The ovaries may respond inadequately to the medications used, which causes the vaccination can not to be made that month.
  • Follicle cracking may be earlier than expected due to an unexpected rise in the LH hormone, which causes the vaccination can not to be made that month.

What is the success rate of vaccination treatment?

The success rate of vaccination treatment is around 15-20%. If number of the male partner’s sperm is within normal limits and the woman’s tubes are healthy, this chance can reach up to 50%.


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